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蛋白质组学及其在重离子治癌应用中的探讨

邴涛 谢漪 党秉荣 杨媛 李文建 张红

邴涛, 谢漪, 党秉荣, 杨媛, 李文建, 张红. 蛋白质组学及其在重离子治癌应用中的探讨[J]. 原子核物理评论, 2005, 22(3): 292-295. doi: 10.11804/NuclPhysRev.22.03.292
引用本文: 邴涛, 谢漪, 党秉荣, 杨媛, 李文建, 张红. 蛋白质组学及其在重离子治癌应用中的探讨[J]. 原子核物理评论, 2005, 22(3): 292-295. doi: 10.11804/NuclPhysRev.22.03.292
Bing Tao, Xie Yi, Dang BingRong, Yang Yuan, Li WenJian, Zhang Gong. Research of Proteomics and Its Application in Tumour Treatment by Heavy Ion[J]. Nuclear Physics Review, 2005, 22(3): 292-295. doi: 10.11804/NuclPhysRev.22.03.292
Citation: Bing Tao, Xie Yi, Dang BingRong, Yang Yuan, Li WenJian, Zhang Gong. Research of Proteomics and Its Application in Tumour Treatment by Heavy Ion[J]. Nuclear Physics Review, 2005, 22(3): 292-295. doi: 10.11804/NuclPhysRev.22.03.292

蛋白质组学及其在重离子治癌应用中的探讨

doi: 10.11804/NuclPhysRev.22.03.292

Research of Proteomics and Its Application in Tumour Treatment by Heavy Ion

  • 摘要: 综述了蛋白质组学的主要方法和技术——双向凝胶电泳、生物质谱技术、蛋白质芯片技术,及其在肿瘤标志物的筛选和鉴定、肿瘤治疗效果的评价及肿瘤发生机制研究等方面的应用状况,并对蛋白质组学在重离子治疗中的应用进行了展望。
    With the accomplishment of the human genome project, proteomics becomes a new snbject on the buildup of the whole proteins and their dynamic changes in cell emerges. Cancer is a kind of complex disease involved in multi-genes and proteins. Heavy ion therapy is all arising and potential radiation treatment nowadays. This paper reviews on the main methods and technology in proteomics-- two-dimensional gel electrophoresis (2-DE),biological mass spectrometry, protein biochips, bioinformatics and its application on identification of cancer biomarkers, evaluation of curative effect on tumour and the mechanisms of turnout formation. This paper also presents some prospects on the application of proteomics in heavv ion therapy.
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出版历程
  • 收稿日期:  1900-01-01
  • 修回日期:  1900-01-01
  • 刊出日期:  2005-09-20

蛋白质组学及其在重离子治癌应用中的探讨

doi: 10.11804/NuclPhysRev.22.03.292

摘要: 综述了蛋白质组学的主要方法和技术——双向凝胶电泳、生物质谱技术、蛋白质芯片技术,及其在肿瘤标志物的筛选和鉴定、肿瘤治疗效果的评价及肿瘤发生机制研究等方面的应用状况,并对蛋白质组学在重离子治疗中的应用进行了展望。
With the accomplishment of the human genome project, proteomics becomes a new snbject on the buildup of the whole proteins and their dynamic changes in cell emerges. Cancer is a kind of complex disease involved in multi-genes and proteins. Heavy ion therapy is all arising and potential radiation treatment nowadays. This paper reviews on the main methods and technology in proteomics-- two-dimensional gel electrophoresis (2-DE),biological mass spectrometry, protein biochips, bioinformatics and its application on identification of cancer biomarkers, evaluation of curative effect on tumour and the mechanisms of turnout formation. This paper also presents some prospects on the application of proteomics in heavv ion therapy.

English Abstract

邴涛, 谢漪, 党秉荣, 杨媛, 李文建, 张红. 蛋白质组学及其在重离子治癌应用中的探讨[J]. 原子核物理评论, 2005, 22(3): 292-295. doi: 10.11804/NuclPhysRev.22.03.292
引用本文: 邴涛, 谢漪, 党秉荣, 杨媛, 李文建, 张红. 蛋白质组学及其在重离子治癌应用中的探讨[J]. 原子核物理评论, 2005, 22(3): 292-295. doi: 10.11804/NuclPhysRev.22.03.292
Bing Tao, Xie Yi, Dang BingRong, Yang Yuan, Li WenJian, Zhang Gong. Research of Proteomics and Its Application in Tumour Treatment by Heavy Ion[J]. Nuclear Physics Review, 2005, 22(3): 292-295. doi: 10.11804/NuclPhysRev.22.03.292
Citation: Bing Tao, Xie Yi, Dang BingRong, Yang Yuan, Li WenJian, Zhang Gong. Research of Proteomics and Its Application in Tumour Treatment by Heavy Ion[J]. Nuclear Physics Review, 2005, 22(3): 292-295. doi: 10.11804/NuclPhysRev.22.03.292

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