2017 Vol. 34, No. 4
Display Method:
2017, 34(4): 699-704.
doi: 10.11804/NuclPhysRev.34.04.699
Abstract:
Isomerism of the high-spin yrast 21/2+ states of the N=51 isotones 91Zr, 93Mo and 95Ru has been investigated using the shell model calculations. It is found that the low-j πp1/2 is responsible for the only yrast trap in 93Mo. In addition, the relatively smaller 101+-121+ level spacing in 94Mo has been found by investigating the systematics of the 101+-121+ level structures in the N=52 isotones 92Zr, 94Mo and 96Ru. This result provides a supplementary argument to the origin of the 21/2+ yrast trap in 93Mo from the viewpoint of the similarity between the configurations of 101+-121+ states in 94Mo and those of 17/21+-21/21+ states in 93Mo.
Isomerism of the high-spin yrast 21/2+ states of the N=51 isotones 91Zr, 93Mo and 95Ru has been investigated using the shell model calculations. It is found that the low-j πp1/2 is responsible for the only yrast trap in 93Mo. In addition, the relatively smaller 101+-121+ level spacing in 94Mo has been found by investigating the systematics of the 101+-121+ level structures in the N=52 isotones 92Zr, 94Mo and 96Ru. This result provides a supplementary argument to the origin of the 21/2+ yrast trap in 93Mo from the viewpoint of the similarity between the configurations of 101+-121+ states in 94Mo and those of 17/21+-21/21+ states in 93Mo.
2017, 34(4): 705-709.
doi: 10.11804/NuclPhysRev.34.04.705
Abstract:
The study of fusion reactions of 12C+13C at the deep sub-barrier energies is very important for the test of predictive power of the extrapolation models for nuclear reactions for astrophysics. Until now, all the measurements below Coulomb barrier energies have to use the statistical model calculations to estimate the branching ratios to deduce the total fusion cross sections. However, the systematic uncertainty induced by the calculated corrections has not been studied well. In this experiment, the fusion cross sections of 12C+13C have been measured using an offline activity measurement in the range of Ec.m.=4.4 to 5.8 MeV. The total fusion cross sections have been deduced from the 24Na activities after correcting the branching ratios estimated with the Hauser-Feshbach statistical model. Through the comparison between our result and other data obtained with other methods, the systematic uncertainty of statistical model has been determined to be 14%.
The study of fusion reactions of 12C+13C at the deep sub-barrier energies is very important for the test of predictive power of the extrapolation models for nuclear reactions for astrophysics. Until now, all the measurements below Coulomb barrier energies have to use the statistical model calculations to estimate the branching ratios to deduce the total fusion cross sections. However, the systematic uncertainty induced by the calculated corrections has not been studied well. In this experiment, the fusion cross sections of 12C+13C have been measured using an offline activity measurement in the range of Ec.m.=4.4 to 5.8 MeV. The total fusion cross sections have been deduced from the 24Na activities after correcting the branching ratios estimated with the Hauser-Feshbach statistical model. Through the comparison between our result and other data obtained with other methods, the systematic uncertainty of statistical model has been determined to be 14%.
2017, 34(4): 710-717.
doi: 10.11804/NuclPhysRev.34.04.710
Abstract:
The author demonstrates that how to understand the Glitches of solid pulsars in the starquake model. Glitch is the sudden spin-up during the normal spin-down process, which has been observed in many pulsars. The mechanism of Glitches is still a matter of debate because it depends on the unsolved problem that what is the nature of pulsars. One of the models of pulsars, the so-called solid quark-cluster stars, could not be ruled out by neither the astrophysics observations nor theoretical considerations. The Glitches of solid quarkcluster stars could naturally be the result of starqukes. During the spinning-down of the solid star, the strain energy develops until the stress reaches the critical value, then some parts of the star fragment, which would suddenly decrease the moment of inertia of the star, leading to the sudden increase of the rotation frequency that manifests as a Glitch. If the star has high mass or rotates slowly, the shrink of radius would happen during the starquake, leading to a huge amount of energy releasing which accounts for AXPs/SGRs. On the other hand, if the star rotates fast, only the oblateness of the star changes during the starquake, which would lead to negligible releasing of energy. This paper discusses the phenomenon of Glitches for solid quark-cluster stars, including the physical processes and consequences of starquakes, as well as the reasons for different energy releasing during Glitches. Further theoretical study combined with more observations about Glitches would be helpful for us to test the conjecture of sold quark-clusters.
The author demonstrates that how to understand the Glitches of solid pulsars in the starquake model. Glitch is the sudden spin-up during the normal spin-down process, which has been observed in many pulsars. The mechanism of Glitches is still a matter of debate because it depends on the unsolved problem that what is the nature of pulsars. One of the models of pulsars, the so-called solid quark-cluster stars, could not be ruled out by neither the astrophysics observations nor theoretical considerations. The Glitches of solid quarkcluster stars could naturally be the result of starqukes. During the spinning-down of the solid star, the strain energy develops until the stress reaches the critical value, then some parts of the star fragment, which would suddenly decrease the moment of inertia of the star, leading to the sudden increase of the rotation frequency that manifests as a Glitch. If the star has high mass or rotates slowly, the shrink of radius would happen during the starquake, leading to a huge amount of energy releasing which accounts for AXPs/SGRs. On the other hand, if the star rotates fast, only the oblateness of the star changes during the starquake, which would lead to negligible releasing of energy. This paper discusses the phenomenon of Glitches for solid quark-cluster stars, including the physical processes and consequences of starquakes, as well as the reasons for different energy releasing during Glitches. Further theoretical study combined with more observations about Glitches would be helpful for us to test the conjecture of sold quark-clusters.
A Calculation Method of Inclusive Electron Nucleus Quasi-elastic Scattering Cross Section at High Q2
2017, 34(4): 718-723.
doi: 10.11804/NuclPhysRev.34.04.718
Abstract:
The electron nucleus collision experiments are approaches measuring the structure of nuclei by using intermediate and high energy probe. This paper shows a calculation method of inclusive electron nucleus quasielastic scattering cross section at high Q2 which based on a empirical formula of Nucleon-Nucleon Short Range Correlation (NN-SRC) and a model of electron deuteron quasi-elastic cross section in Weak-Binding Approximation (WBA). In WBA, the deuteron can be regarded as the combination of quasi-free proton and neutron and the short range correlation between them can be ignored. Therefore the structure function of deuteron can be written as the linear combination of that of proton and neutron, then one can get the cross section of deuteron. According to the cross section of deuteron and the empirical formula, one can obtain the cross section of nuclei A > 2 which considers NN-SRC effect. We compare our calculation results with existing experiments and the results calculated by Bosted' fit method, then find that our results match the experiments at high x and Q2 > 2 GeV2 and better significantly than the Bosted's results for some heavier nucleus, especially 4He.
The electron nucleus collision experiments are approaches measuring the structure of nuclei by using intermediate and high energy probe. This paper shows a calculation method of inclusive electron nucleus quasielastic scattering cross section at high Q2 which based on a empirical formula of Nucleon-Nucleon Short Range Correlation (NN-SRC) and a model of electron deuteron quasi-elastic cross section in Weak-Binding Approximation (WBA). In WBA, the deuteron can be regarded as the combination of quasi-free proton and neutron and the short range correlation between them can be ignored. Therefore the structure function of deuteron can be written as the linear combination of that of proton and neutron, then one can get the cross section of deuteron. According to the cross section of deuteron and the empirical formula, one can obtain the cross section of nuclei A > 2 which considers NN-SRC effect. We compare our calculation results with existing experiments and the results calculated by Bosted' fit method, then find that our results match the experiments at high x and Q2 > 2 GeV2 and better significantly than the Bosted's results for some heavier nucleus, especially 4He.
2017, 34(4): 724-729.
doi: 10.11804/NuclPhysRev.34.04.724
Abstract:
In anlogous to hadron, electron has similar structure because of dressing. So we can define the Transverse Momentum Distribution functions (TMD), the General Parton Distribution functions (GPD) and General Transverse Momentum Distribution functions (GTMD) of electron which come from the Wigner distribution function. The GTMD contain the information of momentum and position of parton in one particle, and the GPD or TMD can be calculated by integration of transverse momentum or setting the transverse transfer momentum which equal to zero. We introduce the light-front wave function of electron to calculate the GTMD of dressed electron, and then get the TMD and GPD. Our results are verified by comparing to calculations in literature and the contribution of GPD of P-wave and S-wave. And we show that the distribution functions at different transverse momentum transfer, transverse momentum of parton and the fraction of longitudinal momentum.
In anlogous to hadron, electron has similar structure because of dressing. So we can define the Transverse Momentum Distribution functions (TMD), the General Parton Distribution functions (GPD) and General Transverse Momentum Distribution functions (GTMD) of electron which come from the Wigner distribution function. The GTMD contain the information of momentum and position of parton in one particle, and the GPD or TMD can be calculated by integration of transverse momentum or setting the transverse transfer momentum which equal to zero. We introduce the light-front wave function of electron to calculate the GTMD of dressed electron, and then get the TMD and GPD. Our results are verified by comparing to calculations in literature and the contribution of GPD of P-wave and S-wave. And we show that the distribution functions at different transverse momentum transfer, transverse momentum of parton and the fraction of longitudinal momentum.
2017, 34(4): 730-734.
doi: 10.11804/NuclPhysRev.34.04.730
Abstract:
Space Environment Simulation and Research Infrastructure (SESRI), which is one of the large-scale scientific projects proposed in National Twelfth Five-Year Plan of China, will be constructed in Harbin Institution of Technology. The SESRI project dedicated to space radiation consists of two ECR ion sources, a high intensity ion linac, a synchrotron and 3 research terminals. As the key part of the complex, a 43.9 m synchrotron can provide broadest energy range and variable ion beam for each terminal. To obtain required intensity in the synchrotron, the injection system is significant. A multi-turn injection scheme is adopted in the synchrotron and the injection process is simulated by ACCSIM with multi-particle tracking method. The results show that the injection efficiency and intensity gain factor can reach 85.5% and 17.1 respectively. The multi-turn injection system can meet the design requirement.
Space Environment Simulation and Research Infrastructure (SESRI), which is one of the large-scale scientific projects proposed in National Twelfth Five-Year Plan of China, will be constructed in Harbin Institution of Technology. The SESRI project dedicated to space radiation consists of two ECR ion sources, a high intensity ion linac, a synchrotron and 3 research terminals. As the key part of the complex, a 43.9 m synchrotron can provide broadest energy range and variable ion beam for each terminal. To obtain required intensity in the synchrotron, the injection system is significant. A multi-turn injection scheme is adopted in the synchrotron and the injection process is simulated by ACCSIM with multi-particle tracking method. The results show that the injection efficiency and intensity gain factor can reach 85.5% and 17.1 respectively. The multi-turn injection system can meet the design requirement.
2017, 34(4): 735-739.
doi: 10.11804/NuclPhysRev.34.04.735
Abstract:
In order to explore the nucleon properties in details, the polarized proton will be used for some special experiments at HIAF project in Institute of Modern Physics, Chinese Academy of Sciences (IMP,CAS). The maximum energy of 9.3 GeV/u for Polarized protons will be provided in the Booster Ring(BRing) at HIAF. The polarized beam experiences depolarizing resonances many times during acceleration process, so it's necessary to suppress those resonances to keep polarizability well by special design. In this paper, the code DEPOL is used to simulate the influence of depolarizing resonances process in BRing. According to the results, the beam's polarization has been destroyed completely by the depolarizing resonances in the acceleration process. And the Full Siberian Snake is chosen in the Electron Cooler part of BRing to preserve the beam's polarization during the acceleration, and its strength and location of the Siberian Snake are also presented here.
In order to explore the nucleon properties in details, the polarized proton will be used for some special experiments at HIAF project in Institute of Modern Physics, Chinese Academy of Sciences (IMP,CAS). The maximum energy of 9.3 GeV/u for Polarized protons will be provided in the Booster Ring(BRing) at HIAF. The polarized beam experiences depolarizing resonances many times during acceleration process, so it's necessary to suppress those resonances to keep polarizability well by special design. In this paper, the code DEPOL is used to simulate the influence of depolarizing resonances process in BRing. According to the results, the beam's polarization has been destroyed completely by the depolarizing resonances in the acceleration process. And the Full Siberian Snake is chosen in the Electron Cooler part of BRing to preserve the beam's polarization during the acceleration, and its strength and location of the Siberian Snake are also presented here.
2017, 34(4): 740-744.
doi: 10.11804/NuclPhysRev.34.04.740
Abstract:
HIAF Fragment Separator(HFRS) is connected with Booster Ring(BRing) and Spectrometer Ring (SRing) in the HIAF and used to transfer the ion beams and radioactive secondary beams. To satisfy the requirements of beam transmission and maintain the extremely high vacuum of BRing and SRing, the average pressure of HFRS vacuum system should be lower than 5×10-7 Pa. Therefore, the feasibility of the design scheme and whether the design scheme would fulfill the required vacuum range or not should be verified. Based on the measured data on the current sychrontron CSRm and the simulation results of BOLIDE, the calculation results of VAKTRAK are verified and then VAKTRAK is used to calculate the pressure profiles of different parameters(such as the conductance, out-gassing and pumping speed) for HFRS. According to the calculation results, the average pressure of HFRS vacuum system could be 1.79×10-7(H2) which achieves the required pressure for physics experiments and engineering design. According the calculation results of this paper, the feasibility of the designed HFRS vacuum system has been verified and the design of system satisfies the vacuum requirements.
HIAF Fragment Separator(HFRS) is connected with Booster Ring(BRing) and Spectrometer Ring (SRing) in the HIAF and used to transfer the ion beams and radioactive secondary beams. To satisfy the requirements of beam transmission and maintain the extremely high vacuum of BRing and SRing, the average pressure of HFRS vacuum system should be lower than 5×10-7 Pa. Therefore, the feasibility of the design scheme and whether the design scheme would fulfill the required vacuum range or not should be verified. Based on the measured data on the current sychrontron CSRm and the simulation results of BOLIDE, the calculation results of VAKTRAK are verified and then VAKTRAK is used to calculate the pressure profiles of different parameters(such as the conductance, out-gassing and pumping speed) for HFRS. According to the calculation results, the average pressure of HFRS vacuum system could be 1.79×10-7(H2) which achieves the required pressure for physics experiments and engineering design. According the calculation results of this paper, the feasibility of the designed HFRS vacuum system has been verified and the design of system satisfies the vacuum requirements.
2017, 34(4): 745-754.
doi: 10.11804/NuclPhysRev.34.04.745
Abstract:
At present, due to the wide application of nuclear and particle physics experiments in the waveform digitization technology and the increasing demand of high speed and high accuracy for ADC, the PCB layout is more and more complex and the cost is higher. In order to simplify the design and reduce the cost, this paper put forward the scheme of JESD204B high speed interface for the waveform digitization technology in nuclear and particle physics experiments. Firstly the interface protocol and the demand of JESD204B is introduced. Then the solution based on Altera FPGA and special JESD204B clock chip LMK0482x is proposed. The preliminary test results show that the clock performance is excellent and JESD204B link is functioning normally. Moreover, the system has an excellent performance. The scheme can realize the design of JESD204B high speed interface and therefore be applied to the waveform digitization technology.
At present, due to the wide application of nuclear and particle physics experiments in the waveform digitization technology and the increasing demand of high speed and high accuracy for ADC, the PCB layout is more and more complex and the cost is higher. In order to simplify the design and reduce the cost, this paper put forward the scheme of JESD204B high speed interface for the waveform digitization technology in nuclear and particle physics experiments. Firstly the interface protocol and the demand of JESD204B is introduced. Then the solution based on Altera FPGA and special JESD204B clock chip LMK0482x is proposed. The preliminary test results show that the clock performance is excellent and JESD204B link is functioning normally. Moreover, the system has an excellent performance. The scheme can realize the design of JESD204B high speed interface and therefore be applied to the waveform digitization technology.
2017, 34(4): 755-761.
doi: 10.11804/NuclPhysRev.34.04.755
Abstract:
Switched Capacitor Arrays (SCAs) can be employed to achieve high speed waveform digitization. In this paper, we designed an 8-channel 2 Gsps waveform digitization module using four SCA chips named FEL_SCA which was designed in our laboratory. In this module, we used a FPGA device for data readout and circuit configuration. Besides, a 128 Mb SDRAM and USB interface were integrated in this module. We have also conducted DC voltage tests, transient tests and bandwidth tests on this module. The results indicate that in the signal voltage range 100 mV~1 V, the INL is better than 1%, the RMS noise is about 1.76 mV and the -3 dB input bandwidth is 450 MHz.
Switched Capacitor Arrays (SCAs) can be employed to achieve high speed waveform digitization. In this paper, we designed an 8-channel 2 Gsps waveform digitization module using four SCA chips named FEL_SCA which was designed in our laboratory. In this module, we used a FPGA device for data readout and circuit configuration. Besides, a 128 Mb SDRAM and USB interface were integrated in this module. We have also conducted DC voltage tests, transient tests and bandwidth tests on this module. The results indicate that in the signal voltage range 100 mV~1 V, the INL is better than 1%, the RMS noise is about 1.76 mV and the -3 dB input bandwidth is 450 MHz.
2017, 34(4): 762-767.
doi: 10.11804/NuclPhysRev.34.04.762
Abstract:
Neutron radiography is an important nondestructive testing technique. It can be used to detect the explosive devices, drug and the nuclear fuel element, etc. A beam-shaping-assembly (BSA) based on a compact D-T neutron generator is designed for fast neutron radiography in this paper. D-T neutron source model is constructed based on the neutron energy spectrum and angular distribution data. The transportation of neutron and γ-ray in the BSA is simulated using MCNP4C code. The neutron fluence of the collimated neutron beam with respect to the neutron source of the unit source is 9.30×10-6 cm-2. The collimated neutron beams is mainly fast neutrons with energies greater than 10 MeV. In the irradiation field range with a diameter of 14 cm, the neutron fluence uniformity of the collimated beam is 4.3%, the ratio of the neutron fluence to the gamma fluence in the collimated beam is 17.20, and the neutron flux and the neutron fluence ratio (J/Φ) is 0.992 which indicates that the collimated neutron beam has good parallelism. The leakage neutron fluence in outside of BSA is two orders of magnitude lower than that of the collimated neutron beam. The designed BSA can meet the need of fast neutron radiography.
Neutron radiography is an important nondestructive testing technique. It can be used to detect the explosive devices, drug and the nuclear fuel element, etc. A beam-shaping-assembly (BSA) based on a compact D-T neutron generator is designed for fast neutron radiography in this paper. D-T neutron source model is constructed based on the neutron energy spectrum and angular distribution data. The transportation of neutron and γ-ray in the BSA is simulated using MCNP4C code. The neutron fluence of the collimated neutron beam with respect to the neutron source of the unit source is 9.30×10-6 cm-2. The collimated neutron beams is mainly fast neutrons with energies greater than 10 MeV. In the irradiation field range with a diameter of 14 cm, the neutron fluence uniformity of the collimated beam is 4.3%, the ratio of the neutron fluence to the gamma fluence in the collimated beam is 17.20, and the neutron flux and the neutron fluence ratio (J/Φ) is 0.992 which indicates that the collimated neutron beam has good parallelism. The leakage neutron fluence in outside of BSA is two orders of magnitude lower than that of the collimated neutron beam. The designed BSA can meet the need of fast neutron radiography.
2017, 34(4): 768-772.
doi: 10.11804/NuclPhysRev.34.04.768
Abstract:
A kind of large position sensitive parallel plate avalanche counter(PPAC) was developed at Gas Detector Research Group, Institute of Modern Physics of CAS. Each of the detector with large sensitive area of 244 mm×284 mm, consists of one central cathode, X anode and Y anode. The cathode plane in the middle of detector is a 1.5 μm thick Mylar foil coated with a thin Au-layer on both sides. The position resolution of the PPAC is better than 4 mm, and the time resolution is 0.42 ns. The detectors were used in the fission experiment with 30MeV/u 40Ar beam bombarding on a gold target to measure the velocity of the fission fragments at Radioactive Ion Beam Line In Lanzhou(RIBLL). Four PPACs were used and the experiment result showed that a rather high detection efficiency (90.3%) is achieved. The position distribution of fission fragments is given by PPACs, which provides very good experimental data for further theoretical analysis.
A kind of large position sensitive parallel plate avalanche counter(PPAC) was developed at Gas Detector Research Group, Institute of Modern Physics of CAS. Each of the detector with large sensitive area of 244 mm×284 mm, consists of one central cathode, X anode and Y anode. The cathode plane in the middle of detector is a 1.5 μm thick Mylar foil coated with a thin Au-layer on both sides. The position resolution of the PPAC is better than 4 mm, and the time resolution is 0.42 ns. The detectors were used in the fission experiment with 30MeV/u 40Ar beam bombarding on a gold target to measure the velocity of the fission fragments at Radioactive Ion Beam Line In Lanzhou(RIBLL). Four PPACs were used and the experiment result showed that a rather high detection efficiency (90.3%) is achieved. The position distribution of fission fragments is given by PPACs, which provides very good experimental data for further theoretical analysis.
2017, 34(4): 773-778.
doi: 10.11804/NuclPhysRev.34.04.773
Abstract:
A new non-intercepting beam profile monitor, residual gas Ionization Profile Monitor (IPM), has been developed and tested at the main Cooling Storage Ring of Heavy Ion Research Facility in Lanzhou (HIRFL-CSRm). It has been successfully used for studies of electron cooling mechanisms, as well as profile monitoring under normal-mode operation in HIRFL-CSRm. The IPM measures the distribution of ions resulting from the residual gas ionization during the beam passage. The gas ions are collected and multiplied by tandem-type MCPs and a phosphor screen, and eventually captured by a commercial CCD camera outside the vacuum chamber. Before formally applied in HIRFL-CSRm, the IPM was tested and compared with a conventional wire scanner profile monitor at Sector Separated Cyclotron Linac (SSC Linac). Both results show good agreement. Besides, the IPM has higher signal to noise ratio than the wire scanner. It also has a very high spatial resolution of around 60 μm. This monitor can be used for low vacuum like Linac with resistance for bias voltage, or for ultra-high vacuum with discrete electrodes for bias voltage where the bakeout process is essential. Furthermore, a novel and compact design of one IPM with capability of detecting both horizontal and vertical profile is proposed. This compact IPM is quite suitable for non-invasive profile diagnostics at space shortage and high-current Linac.
A new non-intercepting beam profile monitor, residual gas Ionization Profile Monitor (IPM), has been developed and tested at the main Cooling Storage Ring of Heavy Ion Research Facility in Lanzhou (HIRFL-CSRm). It has been successfully used for studies of electron cooling mechanisms, as well as profile monitoring under normal-mode operation in HIRFL-CSRm. The IPM measures the distribution of ions resulting from the residual gas ionization during the beam passage. The gas ions are collected and multiplied by tandem-type MCPs and a phosphor screen, and eventually captured by a commercial CCD camera outside the vacuum chamber. Before formally applied in HIRFL-CSRm, the IPM was tested and compared with a conventional wire scanner profile monitor at Sector Separated Cyclotron Linac (SSC Linac). Both results show good agreement. Besides, the IPM has higher signal to noise ratio than the wire scanner. It also has a very high spatial resolution of around 60 μm. This monitor can be used for low vacuum like Linac with resistance for bias voltage, or for ultra-high vacuum with discrete electrodes for bias voltage where the bakeout process is essential. Furthermore, a novel and compact design of one IPM with capability of detecting both horizontal and vertical profile is proposed. This compact IPM is quite suitable for non-invasive profile diagnostics at space shortage and high-current Linac.
2017, 34(4): 779-783.
doi: 10.11804/NuclPhysRev.34.04.779
Abstract:
The breeding method by low-energy ion implantation has been proved to be a valuable breeding method by a large number of practical attempts, but the mechanism of the method has always been in a large dispute. The most difficult thing to be understood is how the low energy heavy ion with such a short range (normally shorter than 1 μm) can penetrate into the inner part of seeds to trigger the biological effects. In this paper, simulations with quantitative analysis were performed for the low energy ion implantating into biological samples and the effects caused by the secondary particles using SRIM, CASINO and Geant4 simulation programs. The results showed that the ranges of low energy heavy ions are normally less than 1 μm. The ranges can become longer if dry seeds and light ions are used with a higher energy. The ranges of recoil protons are only a little longer than that of the primary ions. Among the secondary particles produced in the ion implanting process, only the X-ray can obviously increase the penetration depth in seeds. There always will be a small amount of X-rays which can penetrate into the deeper place in the seed if the ion dose is high enough.
The breeding method by low-energy ion implantation has been proved to be a valuable breeding method by a large number of practical attempts, but the mechanism of the method has always been in a large dispute. The most difficult thing to be understood is how the low energy heavy ion with such a short range (normally shorter than 1 μm) can penetrate into the inner part of seeds to trigger the biological effects. In this paper, simulations with quantitative analysis were performed for the low energy ion implantating into biological samples and the effects caused by the secondary particles using SRIM, CASINO and Geant4 simulation programs. The results showed that the ranges of low energy heavy ions are normally less than 1 μm. The ranges can become longer if dry seeds and light ions are used with a higher energy. The ranges of recoil protons are only a little longer than that of the primary ions. Among the secondary particles produced in the ion implanting process, only the X-ray can obviously increase the penetration depth in seeds. There always will be a small amount of X-rays which can penetrate into the deeper place in the seed if the ion dose is high enough.
2017, 34(4): 784-789.
doi: 10.11804/NuclPhysRev.34.04.784
Abstract:
Short treatment course due to the suitability of hypofractionated regimen for carbon ion beam is one of the advantages of carbon ion radiotherapy. To study the dependence of relative biological effectiveness (RBE) on dose, the relationship between RBE and dose was deduced through the linear-quadratic (LQ) model. Based on the relationship, the change of RBE of tumor cells and normal tissue cells with different radiosensitivities with dose was studied. The results showed that the RBE value of tumor cells was always greater than that of normal tissue cells in the dose range of 0~20 Gy, regardless of the radiosensitivity of tumor and normal tissue cells. In addition, based on theoretical deduction and analysis of the relevant experimental data, the existence of RBE increase with increasing dose was verified. These results are of great significance for conducting hypofractionated radiotherapy with carbon ion beam.
Short treatment course due to the suitability of hypofractionated regimen for carbon ion beam is one of the advantages of carbon ion radiotherapy. To study the dependence of relative biological effectiveness (RBE) on dose, the relationship between RBE and dose was deduced through the linear-quadratic (LQ) model. Based on the relationship, the change of RBE of tumor cells and normal tissue cells with different radiosensitivities with dose was studied. The results showed that the RBE value of tumor cells was always greater than that of normal tissue cells in the dose range of 0~20 Gy, regardless of the radiosensitivity of tumor and normal tissue cells. In addition, based on theoretical deduction and analysis of the relevant experimental data, the existence of RBE increase with increasing dose was verified. These results are of great significance for conducting hypofractionated radiotherapy with carbon ion beam.
2017, 34(4): 790-796.
doi: 10.11804/NuclPhysRev.34.04.790
Abstract:
Histone acetylation is one of important epigenetic modifications, and histone in most of tumor cells shows low acetylation state. However, histone deacetylase inhibitor (HDACi) can correct abnormal acetylation status, induce cell cycle arrest and apoptosis. Trichostatin A (TSA) is one of the representatives of histone deacetylase inhibitors, which can inhibit histone deacetylase, increase the acetylation level of histone and nonhistone in cell. Fourier transform infrared (FTIR) spectroscopy is a powerful analytical tool which can detect nondestructively, quatitatively and quantitatively biological samples without bio-tagging and bio-labeling. FTIR spectroscopy technology has multiple advantages, including finger-print characteristics, rapid analysis, high resolution and good repeatability. Therefore, it has been widely used in the research of biological processes. This work applied FTIR spectroscopy to study the changes in cells treated with TSA, compared the acetylation level according to FTIR intensity ratio of methyl to methylene stretching vibration, and based on the FTIR analysis predicted the radiosensitivity of the cells with different acetylation levels. As a result, we have verified that the damage caused by radiation in acetylated cells can be evaluated by the ratio of methyl and methylene intensity which is positively correlated with cellular radiosensitivity. Therefore, this work demonstrates that FTIR spectroscopy can be useful for the prediction of radiosensitivity and may also open a door for the study of relationship between epigenetics and radiation bio-effects.
Histone acetylation is one of important epigenetic modifications, and histone in most of tumor cells shows low acetylation state. However, histone deacetylase inhibitor (HDACi) can correct abnormal acetylation status, induce cell cycle arrest and apoptosis. Trichostatin A (TSA) is one of the representatives of histone deacetylase inhibitors, which can inhibit histone deacetylase, increase the acetylation level of histone and nonhistone in cell. Fourier transform infrared (FTIR) spectroscopy is a powerful analytical tool which can detect nondestructively, quatitatively and quantitatively biological samples without bio-tagging and bio-labeling. FTIR spectroscopy technology has multiple advantages, including finger-print characteristics, rapid analysis, high resolution and good repeatability. Therefore, it has been widely used in the research of biological processes. This work applied FTIR spectroscopy to study the changes in cells treated with TSA, compared the acetylation level according to FTIR intensity ratio of methyl to methylene stretching vibration, and based on the FTIR analysis predicted the radiosensitivity of the cells with different acetylation levels. As a result, we have verified that the damage caused by radiation in acetylated cells can be evaluated by the ratio of methyl and methylene intensity which is positively correlated with cellular radiosensitivity. Therefore, this work demonstrates that FTIR spectroscopy can be useful for the prediction of radiosensitivity and may also open a door for the study of relationship between epigenetics and radiation bio-effects.
2017, 34(4): 797-802.
doi: 10.11804/NuclPhysRev.34.04.797
Abstract:
This study aims to investigate the effect of carboxymethy-β-1, 3-glucan (CMG) on the sensitivity of human hepatoma HepG2 cells to X-rays or 12C6+ ions irradiation. First, the inhibitory effect of CMG on the growth of HepG2 cells was detected by CCK-8 assay, and the half maximal inhibitory concentration (IC50) was 120.6 μg/mL. HepG2 cells were pretreated with CMG at a concentration of 0.1×IC50 for 24 h and then irradiated with 2 Gy X-ray or 12C6+ ion beams (CMG + irradiation group). CMG untreated group was directly irradiated by 2 Gy X-rays or 12C6+ ions beam (irradiation group). The clone survival, DNA damage, cell apoptosis, cell cycle distribution, and intracellular reactive oxygen species (ROS) levels in irradiation group and CMG + irradiation group were comparatively analyzed. The results showed that the clone survival rate was lower, DNA damage and cycle arrest were more serious, and the rate of apoptosis and intracellular ROS levels were higher in 12C6+ ions irradiation group than those in the same dose of X-rays irradiation group. Compared with X-rays or 12C6+ ions irradiation group, the clone survival rate of CMG + irradiation group was significantly decreased, and the apoptosis rate significantly increased with the prolongation of CMG treatment post-irradiation; CMG maintained intracellular ROS at a higher level after irradiation, CMG also significantly aggravated radiation-induced DNA damage and cycle arrest. These results indicated that HepG2 cells were more sensitive to 12C6+ ions radiation than those at the same dose of X-rays. CMG increased the sensitivity of HepG2 cells to X-rays or 12C6+ ions irradiation by increasing intracellular ROS level, exacerbating radiation-induced DNA damage and promoting radiation-induced apoptosis in irradiated HepG2 cells.
This study aims to investigate the effect of carboxymethy-β-1, 3-glucan (CMG) on the sensitivity of human hepatoma HepG2 cells to X-rays or 12C6+ ions irradiation. First, the inhibitory effect of CMG on the growth of HepG2 cells was detected by CCK-8 assay, and the half maximal inhibitory concentration (IC50) was 120.6 μg/mL. HepG2 cells were pretreated with CMG at a concentration of 0.1×IC50 for 24 h and then irradiated with 2 Gy X-ray or 12C6+ ion beams (CMG + irradiation group). CMG untreated group was directly irradiated by 2 Gy X-rays or 12C6+ ions beam (irradiation group). The clone survival, DNA damage, cell apoptosis, cell cycle distribution, and intracellular reactive oxygen species (ROS) levels in irradiation group and CMG + irradiation group were comparatively analyzed. The results showed that the clone survival rate was lower, DNA damage and cycle arrest were more serious, and the rate of apoptosis and intracellular ROS levels were higher in 12C6+ ions irradiation group than those in the same dose of X-rays irradiation group. Compared with X-rays or 12C6+ ions irradiation group, the clone survival rate of CMG + irradiation group was significantly decreased, and the apoptosis rate significantly increased with the prolongation of CMG treatment post-irradiation; CMG maintained intracellular ROS at a higher level after irradiation, CMG also significantly aggravated radiation-induced DNA damage and cycle arrest. These results indicated that HepG2 cells were more sensitive to 12C6+ ions radiation than those at the same dose of X-rays. CMG increased the sensitivity of HepG2 cells to X-rays or 12C6+ ions irradiation by increasing intracellular ROS level, exacerbating radiation-induced DNA damage and promoting radiation-induced apoptosis in irradiated HepG2 cells.
2017, 34(4): 803-810.
doi: 10.11804/NuclPhysRev.34.04.803
Abstract:
Because of the similarity in cascade damage structure in materials produced by energetic heavy ions and by fast neutrons, and the high displacement rate and low induced radioactivity of samples by heavy ions, heavy ion beam becomes an important tool to simulate radiation damage by energetic neutrons in materials in advanced nuclear energy systems. The ranges of heavy ions provided by HIRFL (Heavy Ion Research Facility in Lanzhou) are generally much larger than the mean dimensions of grains in alloys candidate to advanced nuclear reactors, and is capable of producing radiation damage in bulk scale. It therefore makes possible the evaluation of change of mechanical properties including the radiation induced embrittlement from the irradiated specimens by using miniaturized specimen techniques. In the present paper, we provide an introduction of our recent studies of radiation damage of materials candidate to future fusion reactors by utilizing heavy ion beams in HIRFL.The studies include issues as follows:ductility loss of RAFM steels causes by high-energy Ne ions, impact of oxide dispersoids on the radiation resistance of ODS ferritic steels, correlation of void swelling of ferritic/martensitic steels under different particle irradiation, and behavior of deuterium retention in tungsten under irradiation with high-energy heavy ions. The results show that high-energy heavy ions can be used as a tool to efficiently investigate or evaluate radiation damage in structure materials if combined with some special test techniques and data analysis.
Because of the similarity in cascade damage structure in materials produced by energetic heavy ions and by fast neutrons, and the high displacement rate and low induced radioactivity of samples by heavy ions, heavy ion beam becomes an important tool to simulate radiation damage by energetic neutrons in materials in advanced nuclear energy systems. The ranges of heavy ions provided by HIRFL (Heavy Ion Research Facility in Lanzhou) are generally much larger than the mean dimensions of grains in alloys candidate to advanced nuclear reactors, and is capable of producing radiation damage in bulk scale. It therefore makes possible the evaluation of change of mechanical properties including the radiation induced embrittlement from the irradiated specimens by using miniaturized specimen techniques. In the present paper, we provide an introduction of our recent studies of radiation damage of materials candidate to future fusion reactors by utilizing heavy ion beams in HIRFL.The studies include issues as follows:ductility loss of RAFM steels causes by high-energy Ne ions, impact of oxide dispersoids on the radiation resistance of ODS ferritic steels, correlation of void swelling of ferritic/martensitic steels under different particle irradiation, and behavior of deuterium retention in tungsten under irradiation with high-energy heavy ions. The results show that high-energy heavy ions can be used as a tool to efficiently investigate or evaluate radiation damage in structure materials if combined with some special test techniques and data analysis.
2017, 34(4): 811-814.
doi: 10.11804/NuclPhysRev.34.04.811
Abstract:
The Misconstructural damage of GaP irradiated with 56Fe13+ to fluences ranging from 1×107 ions/cm2~1×1010 ions/cm2 were analyzed by X-ray diffraction (XRD) techniques, Fourier transform infrared spectroscopy (FTIR) and Raman spectroscopy. The result shows that, with the increase of irradiation ion fluences, local disorder and defects were produced in GaP crystal. With the increase of ion fluence, Raman spectra reveal the intensity of scattering peaks gradually weakens and some scattering peaks gradually disappear, however no changes in the peak position were found. XRD measurement displays that the intensity of diffraction peaks gradually decreases with an increase in ions fluences. Result from FTIR spectra exhibits that the intensity of reflection peaks gradually increases and the FWHM of reflection peaks broadens. These phenomena indicate that, the irradiation of heavy-ion Fe produces defects and disorder in GaP crystal, leading to a local amorphization.
The Misconstructural damage of GaP irradiated with 56Fe13+ to fluences ranging from 1×107 ions/cm2~1×1010 ions/cm2 were analyzed by X-ray diffraction (XRD) techniques, Fourier transform infrared spectroscopy (FTIR) and Raman spectroscopy. The result shows that, with the increase of irradiation ion fluences, local disorder and defects were produced in GaP crystal. With the increase of ion fluence, Raman spectra reveal the intensity of scattering peaks gradually weakens and some scattering peaks gradually disappear, however no changes in the peak position were found. XRD measurement displays that the intensity of diffraction peaks gradually decreases with an increase in ions fluences. Result from FTIR spectra exhibits that the intensity of reflection peaks gradually increases and the FWHM of reflection peaks broadens. These phenomena indicate that, the irradiation of heavy-ion Fe produces defects and disorder in GaP crystal, leading to a local amorphization.
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