初步的IMP重离子治疗计划系统

刘新国; 李强; #; 杜晓刚; 王阳萍; 戴中颖; 叶飞; 吴庆丰; 金晓东; 李萍; 党建武

doi:10.11804/NuclPhysRev.27.04.480

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初步的IMP重离子治疗计划系统

刘新国, 李强, #, 杜晓刚, 王阳萍, 戴中颖, 叶飞, 吴庆丰, 金晓东, 李萍, 党建武

文章导航 > 原子核物理评论 > 2010 > 27(4): 480-487

刘新国, 李强, #, 杜晓刚, 王阳萍, 戴中颖, 叶飞, 吴庆丰, 金晓东, 李萍, 党建武. 初步的IMP重离子治疗计划系统[J]. 原子核物理评论, 2010, 27(4): 480-487. doi: 10.11804/NuclPhysRev.27.04.480

引用本文:

LIU Xin-guo, LI Qiang, #, DU Xiao-gang, WANG Yang-ping, DAI Zhong-ying, YE Fei, WU Qing-feng, JIN Xiao-dong, . A Preliminary Version of Heavy Ion Treatment Planning System at IMP[J]. Nuclear Physics Review, 2010, 27(4): 480-487. doi: 10.11804/NuclPhysRev.27.04.480

Citation:

LIU Xin-guo, LI Qiang, #, DU Xiao-gang, WANG Yang-ping, DAI Zhong-ying, YE Fei, WU Qing-feng, JIN Xiao-dong, . A Preliminary Version of Heavy Ion Treatment Planning System at IMP[J]. Nuclear Physics Review, 2010, 27(4): 480-487. doi: 10.11804/NuclPhysRev.27.04.480

初步的IMP重离子治疗计划系统

doi: 10.11804/NuclPhysRev.27.04.480

1中国科学院近代物理研究所, 甘肃兰州 730000;2中国科学院重离子束辐射生物医学重点实验室, 甘肃兰州 730000;3中国科学院研究生院, 北京 100049;4兰州交通大学电子与信息工程学院, 甘肃兰州 730070

A Preliminary Version of Heavy Ion Treatment Planning System at IMP

1 Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China;2 Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou 730000, China;3 Graduate University of Chinese Academy of Sciences, Beijing 100049, China;4 School of Electronic & Information Engineering, Lanzhou Jiaotong University, Lanzhou 730070, China

摘要: 中国科学院近代物理研究所基于兰州重离子研究装置（HIRFL/HIRFL-CSR），在被动型束流配送系统下采用二维分层适形照射治疗技术开展重离子治癌临床试验研究。为了更好地利用重离子束在肿瘤放射治疗中的生物物理优势并保障重离子临床治疗试验的顺利实施，一个初级版本的重离子治疗计划系统已经设计完成。此计划系统是针对被动型束流配送系统下的二维分层适形照射治疗方式来进行设计的。介绍了此系统的设计框架、可提供的功能以及利用宽束算法进行剂量计算在此系统中的实现。通过人体仿真体模实验证实由该治疗计划系统给出的靶区计划剂量与实测剂量的偏差在5%之内。最后讨论了设计较为完备的重离子治疗计划系统仍需解决的问题。 Based on the Heavy Ion Research Facility in Lanzhou(HIRFL/HIRFLCSR)， clinical trials of heavy ion radiotherapy are being conducted at the〖HJ*4/9〗 Institute of Modern Physics(IMP)， Chinese Academy of Sciences， where twodimensional(2D) layerstacking conformal irradiation method in a passive beam delivery system was applied. To make better use of the biophysical advantages of heavy ion beams and ensure success of the clinical trials， a preliminary version of heavy ion treatment planning system(TPS) has been developed at IMP. The TPS was designed in a manner to adapt to the 2D layerstacking conformal irradiation method. The architecture and function of the TPS software and the implementation 〖HJ〗of dose calculation algorithm in the TPS were introduced in this paper. The deviation between the doses planned by the TPS and measured through an anthropomorphous phantom was verified to be less than 5%. Finally， the pending issues for developing a sophisticated treatment planning system at IMP were discussed.
- 重离子治癌 /
- 治疗计划系统 /
- 二维分层适形照射 /
- 剂量算法
Abstract: Based on the Heavy Ion Research Facility in Lanzhou(HIRFL/HIRFLCSR)， clinical trials of heavy ion radiotherapy are being conducted at the〖HJ*4/9〗 Institute of Modern Physics(IMP)， Chinese Academy of Sciences， where twodimensional(2D) layerstacking conformal irradiation method in a passive beam delivery system was applied. To make better use of the biophysical advantages of heavy ion beams and ensure success of the clinical trials， a preliminary version of heavy ion treatment planning system(TPS) has been developed at IMP. The TPS was designed in a manner to adapt to the 2D layerstacking conformal irradiation method. The architecture and function of the TPS software and the implementation 〖HJ〗of dose calculation algorithm in the TPS were introduced in this paper. The deviation between the doses planned by the TPS and measured through an anthropomorphous phantom was verified to be less than 5%. Finally， the pending issues for developing a sophisticated treatment planning system at IMP were discussed.

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初步的IMP重离子治疗计划系统

doi: 10.11804/NuclPhysRev.27.04.480

1中国科学院近代物理研究所, 甘肃兰州 730000;2中国科学院重离子束辐射生物医学重点实验室, 甘肃兰州 730000;3中国科学院研究生院, 北京 100049;4兰州交通大学电子与信息工程学院, 甘肃兰州 730070

收稿日期: 1900-01-01
修回日期: 1900-01-01
刊出日期: 2010-12-20

关键词:

摘要: 中国科学院近代物理研究所基于兰州重离子研究装置（HIRFL/HIRFL-CSR），在被动型束流配送系统下采用二维分层适形照射治疗技术开展重离子治癌临床试验研究。为了更好地利用重离子束在肿瘤放射治疗中的生物物理优势并保障重离子临床治疗试验的顺利实施，一个初级版本的重离子治疗计划系统已经设计完成。此计划系统是针对被动型束流配送系统下的二维分层适形照射治疗方式来进行设计的。介绍了此系统的设计框架、可提供的功能以及利用宽束算法进行剂量计算在此系统中的实现。通过人体仿真体模实验证实由该治疗计划系统给出的靶区计划剂量与实测剂量的偏差在5%之内。最后讨论了设计较为完备的重离子治疗计划系统仍需解决的问题。 Based on the Heavy Ion Research Facility in Lanzhou(HIRFL/HIRFLCSR)， clinical trials of heavy ion radiotherapy are being conducted at the〖HJ*4/9〗 Institute of Modern Physics(IMP)， Chinese Academy of Sciences， where twodimensional(2D) layerstacking conformal irradiation method in a passive beam delivery system was applied. To make better use of the biophysical advantages of heavy ion beams and ensure success of the clinical trials， a preliminary version of heavy ion treatment planning system(TPS) has been developed at IMP. The TPS was designed in a manner to adapt to the 2D layerstacking conformal irradiation method. The architecture and function of the TPS software and the implementation 〖HJ〗of dose calculation algorithm in the TPS were introduced in this paper. The deviation between the doses planned by the TPS and measured through an anthropomorphous phantom was verified to be less than 5%. Finally， the pending issues for developing a sophisticated treatment planning system at IMP were discussed.

English Abstract

A Preliminary Version of Heavy Ion Treatment Planning System at IMP

1 Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China;2 Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou 730000, China;3 Graduate University of Chinese Academy of Sciences, Beijing 100049, China;4 School of Electronic & Information Engineering, Lanzhou Jiaotong University, Lanzhou 730070, China

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2010-12-20

Abstract: Based on the Heavy Ion Research Facility in Lanzhou(HIRFL/HIRFLCSR)， clinical trials of heavy ion radiotherapy are being conducted at the〖HJ*4/9〗 Institute of Modern Physics(IMP)， Chinese Academy of Sciences， where twodimensional(2D) layerstacking conformal irradiation method in a passive beam delivery system was applied. To make better use of the biophysical advantages of heavy ion beams and ensure success of the clinical trials， a preliminary version of heavy ion treatment planning system(TPS) has been developed at IMP. The TPS was designed in a manner to adapt to the 2D layerstacking conformal irradiation method. The architecture and function of the TPS software and the implementation 〖HJ〗of dose calculation algorithm in the TPS were introduced in this paper. The deviation between the doses planned by the TPS and measured through an anthropomorphous phantom was verified to be less than 5%. Finally， the pending issues for developing a sophisticated treatment planning system at IMP were discussed.

引用本文:

Citation:

LIU Xin-guo, LI Qiang, #, DU Xiao-gang, WANG Yang-ping, DAI Zhong-ying, YE Fei, WU Qing-feng, JIN Xiao-dong, . A Preliminary Version of Heavy Ion Treatment Planning System at IMP[J]. Nuclear Physics Review, 2010, 27(4): 480-487. doi: 10.11804/NuclPhysRev.27.04.480