Brief Review of Nuclear Pharmaceutical Study at IHIP

Wagn Xiang-yun

doi:10.11804/NuclPhysRev.13.02.060

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Volume 13 Issue 2

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Article Navigation > Nuclear Physics Review > 1996 > 13(2): 60-61

Wagn Xiang-yun. Brief Review of Nuclear Pharmaceutical Study at IHIP[J]. Nuclear Physics Review, 1996, 13(2): 60-61. doi: 10.11804/NuclPhysRev.13.02.060

Citation:

Wagn Xiang-yun. Brief Review of Nuclear Pharmaceutical Study at IHIP[J]. Nuclear Physics Review, 1996, 13(2): 60-61. doi: 10.11804/NuclPhysRev.13.02.060

Brief Review of Nuclear Pharmaceutical Study at IHIP

doi: 10.11804/NuclPhysRev.13.02.060

Wagn Xiang-yun

Department of Technical Physics; Institute of Heavy Ion Physics; Peking University; Beijing 100871

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 1996-06-20

Abstract

The labeling of anti tumor monoclonalantibodies (McAB) with radionuclides has been regarded as our main aim in the past 12 years. A procedure of preparation of ultrapure carrier free 111 In has been developed. Anti tumor McABs labeled with 111 In via a bifunctional conjugating agent (DTPA cycloanhydride) were used successfully in clinical trials. 99m Tc labeled McAB fragments prepared by a direct method were also proved very powerful in diagnosis of gastric carcinoma...
- nuclear pharmaceutical,
- radioactive labeling,
- monoclonal antibody,
- accelerator mass spectroscopy,
- genetic toxicity
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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Brief Review of Nuclear Pharmaceutical Study at IHIP

doi: 10.11804/NuclPhysRev.13.02.060

Wagn Xiang-yun

Department of Technical Physics; Institute of Heavy Ion Physics; Peking University; Beijing 100871

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 1996-06-20

Key words:

Abstract: The labeling of anti tumor monoclonalantibodies (McAB) with radionuclides has been regarded as our main aim in the past 12 years. A procedure of preparation of ultrapure carrier free 111 In has been developed. Anti tumor McABs labeled with 111 In via a bifunctional conjugating agent (DTPA cycloanhydride) were used successfully in clinical trials. 99m Tc labeled McAB fragments prepared by a direct method were also proved very powerful in diagnosis of gastric carcinoma...

Wagn Xiang-yun. Brief Review of Nuclear Pharmaceutical Study at IHIP[J]. Nuclear Physics Review, 1996, 13(2): 60-61. doi: 10.11804/NuclPhysRev.13.02.060

Citation:

Wagn Xiang-yun. Brief Review of Nuclear Pharmaceutical Study at IHIP[J]. Nuclear Physics Review, 1996, 13(2): 60-61. doi: 10.11804/NuclPhysRev.13.02.060