A New Method for Calculating Yield of DNA Double-strand Breaks

ZHOU Guang-ming; LI Wen-jian; GAO Qing-xiang; WEI Zeng-quan

doi:10.11804/NuclPhysRev.20.01.052

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Article Navigation > Nuclear Physics Review > 2003 > 20(1): 52-54

ZHOU Guang-ming, LI Wen-jian, GAO Qing-xiang, WEI Zeng-quan. A New Method for Calculating Yield of DNA Double-strand Breaks[J]. Nuclear Physics Review, 2003, 20(1): 52-54. doi: 10.11804/NuclPhysRev.20.01.052

Citation:

ZHOU Guang-ming, LI Wen-jian, GAO Qing-xiang, WEI Zeng-quan. A New Method for Calculating Yield of DNA Double-strand Breaks[J]. Nuclear Physics Review, 2003, 20(1): 52-54. doi: 10.11804/NuclPhysRev.20.01.052

A New Method for Calculating Yield of DNA Double-strand Breaks

doi: 10.11804/NuclPhysRev.20.01.052

1 Institute of Modern Physics; Chinese Academy of Sciences; Lanzhou 730000; China; 2 School of Life Science; Lanzhou University; China);

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2003-03-20

Abstract

Quantitive analysis of DNA doublestrand break (DSB) is of importance for studying on the mechanisms of radiobiological effects induced by high linear energy transfer(LET) irradiation. For the practical use, one new calculating formula named the method of average molecular weight is deducted. In this method, the factual distribution of DSB fragments is not considered, but actually, the content and distribution of DSB fragments are included. Totally, this method is simple in shape and easy to use, esp...
- DNA double-strand break,
- high linear energy transfer irradiation,
- biological effect,
- calculating method
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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