Biological Effect Induced by Radioactive Ion Beam and Corresponding Biophysical Mechanisms

LI Qiang; Y.Furusawa; A.Kitagawa; M.Kanazawa; JIN Xiao-dong; DAI Zhong-ying

doi:10.11804/NuclPhysRev.24.02.089

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Volume 24 Issue 2

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Article Navigation > Nuclear Physics Review > 2007 > 24(2): 89-93

LI Qiang, Y.Furusawa, A.Kitagawa, M.Kanazawa, JIN Xiao-dong, DAI Zhong-ying. Biological Effect Induced by Radioactive Ion Beam and Corresponding Biophysical Mechanisms[J]. Nuclear Physics Review, 2007, 24(2): 89-93. doi: 10.11804/NuclPhysRev.24.02.089

Citation:

LI Qiang, Y.Furusawa, A.Kitagawa, M.Kanazawa, JIN Xiao-dong, DAI Zhong-ying. Biological Effect Induced by Radioactive Ion Beam and Corresponding Biophysical Mechanisms[J]. Nuclear Physics Review, 2007, 24(2): 89-93. doi: 10.11804/NuclPhysRev.24.02.089

Biological Effect Induced by Radioactive Ion Beam and Corresponding Biophysical Mechanisms

doi: 10.11804/NuclPhysRev.24.02.089

1 Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China; 2 National Institute of Radiological Sciences, Chiba 2638555, Japan

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2007-06-20

Abstract

The depthsurvival effect of a βdelayed particle decay 9C beam on human salivary gland (HSG) cells is presented in this paper. Compared with a stable 12Cion beam， the radioactive 9Cion beam showed an enhanced biological effect， i.e.， remarkably enhanced efficiency in cell killing， at the penetration depths around its Bragg peak. The biophysical mechanisms underlying the enhanced biological effect are discussed herein， and the latest progress in biological effect induced by another radioactive 8Bion beam is introduced. In the end of this paper， several topics concerning the frontier of the radiationinduced biological effects using radioactive ion beams are proposed.
- radioactive ion beam,
- 9C ion beam,
- enhanced biological effect,
- biophysical mechanism
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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Biological Effect Induced by Radioactive Ion Beam and Corresponding Biophysical Mechanisms

doi: 10.11804/NuclPhysRev.24.02.089

1 Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China; 2 National Institute of Radiological Sciences, Chiba 2638555, Japan

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2007-06-20

Key words:

Abstract: The depthsurvival effect of a βdelayed particle decay 9C beam on human salivary gland (HSG) cells is presented in this paper. Compared with a stable 12Cion beam， the radioactive 9Cion beam showed an enhanced biological effect， i.e.， remarkably enhanced efficiency in cell killing， at the penetration depths around its Bragg peak. The biophysical mechanisms underlying the enhanced biological effect are discussed herein， and the latest progress in biological effect induced by another radioactive 8Bion beam is introduced. In the end of this paper， several topics concerning the frontier of the radiationinduced biological effects using radioactive ion beams are proposed.

Citation:

LI Qiang, Y.Furusawa, A.Kitagawa, M.Kanazawa, JIN Xiao-dong, DAI Zhong-ying. Biological Effect Induced by Radioactive Ion Beam and Corresponding Biophysical Mechanisms[J]. Nuclear Physics Review, 2007, 24(2): 89-93. doi: 10.11804/NuclPhysRev.24.02.089