Molecular Mechanism of Mutagenesis and Interaction of Incident Ions with Organism Implanted by Heavy Ions Beam

LI Ke; ZHANG Dong-zheng; ZHAO Jin; ZHANG Gen-fa; #

doi:10.11804/NuclPhysRev.24.02.117

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Article Navigation > Nuclear Physics Review > 2007 > 24(2): 117-123

LI Ke, ZHANG Dong-zheng, ZHAO Jin, ZHANG Gen-fa, #. Molecular Mechanism of Mutagenesis and Interaction of Incident Ions with Organism Implanted by Heavy Ions Beam[J]. Nuclear Physics Review, 2007, 24(2): 117-123. doi: 10.11804/NuclPhysRev.24.02.117

Citation:

LI Ke, ZHANG Dong-zheng, ZHAO Jin, ZHANG Gen-fa, #. Molecular Mechanism of Mutagenesis and Interaction of Incident Ions with Organism Implanted by Heavy Ions Beam[J]. Nuclear Physics Review, 2007, 24(2): 117-123. doi: 10.11804/NuclPhysRev.24.02.117

Molecular Mechanism of Mutagenesis and Interaction of Incident Ions with Organism Implanted by Heavy Ions Beam

doi: 10.11804/NuclPhysRev.24.02.117

1 College of Life Sciences, Beijing Normal University, Beijing 100875, China; 2 Department of Physics, Shanghai Jiaotong University, Shanghai 200030, China

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2007-06-20

Abstract

As a new mutagenesis technique, low energy heavy ion implantation started in China for the study of interaction effect between incident ions and organism, and great achievements have been obtained in crop breeding. The article reviewed the main biological effects induced by heavy ion implantation, including physiology, biochemistry and genetics effects, on levels of cell and chromosome, gene expression, DNA methylation, DNA damage and reparation etc. It compared the differences in mutagenesis for organism by high energy and low energy ion implantation, as well as γ ray radiaiton. Future investigation topics were proposed, the emphasis of researches in future was pointed out, i.e., the molecular mechanism and effects of gene differential expression of organism treated by ion implantation.
- ion implantation,
- DNA damage and reparation,
- DNA modification,
- genetic mutagenesis,
- mutation hot site
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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Molecular Mechanism of Mutagenesis and Interaction of Incident Ions with Organism Implanted by Heavy Ions Beam

doi: 10.11804/NuclPhysRev.24.02.117

1 College of Life Sciences, Beijing Normal University, Beijing 100875, China; 2 Department of Physics, Shanghai Jiaotong University, Shanghai 200030, China

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2007-06-20

Key words:

Abstract: As a new mutagenesis technique, low energy heavy ion implantation started in China for the study of interaction effect between incident ions and organism, and great achievements have been obtained in crop breeding. The article reviewed the main biological effects induced by heavy ion implantation, including physiology, biochemistry and genetics effects, on levels of cell and chromosome, gene expression, DNA methylation, DNA damage and reparation etc. It compared the differences in mutagenesis for organism by high energy and low energy ion implantation, as well as γ ray radiaiton. Future investigation topics were proposed, the emphasis of researches in future was pointed out, i.e., the molecular mechanism and effects of gene differential expression of organism treated by ion implantation.

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