Progress in hprt Mutation Assay and Its Application in Radiation Biology
doi: 10.11804/NuclPhysRev.25.03.294
- Received Date: 1900-01-01
- Rev Recd Date: 1900-01-01
- Publish Date: 2008-09-20
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Key words:
- hprt gene /
- mutation detection /
- radiation biology
Abstract: hprt gene is an Xlinked locus that has been well studied and widely used as a biomarker in mutation detection. hprt mutation assay is a gene mutation test system in mammalian cells in vitro which has been used as a biological dosimeter. In this paper, the biological characteristics of hprt gene, hprt mutation detection methodology and the application of hprt mutation assay in radiation biology are comprehensively reviewed.
Citation: | HE Jing, LI Qiang. Progress in hprt Mutation Assay and Its Application in Radiation Biology[J]. Nuclear Physics Review, 2008, 25(3): 294-299. doi: 10.11804/NuclPhysRev.25.03.294 |