Protective  Effect  of  Yeast  β-glucan  on  Immune  System  of  Mice  Irradiated  by  Carbon  Ions

WANG  Ying; LU  Dong; WEI  Wei; JING  Xi-gang; WANG  Ju-fang; LI  Wen-jian

doi:10.11804/NuclPhysRev.29.03.285

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Article Navigation > Nuclear Physics Review > 2012 > 29(3): 285-289

WANG Ying, LU Dong, WEI Wei, JING Xi-gang, WANG Ju-fang, LI Wen-jian. Protective Effect of Yeast β-glucan on Immune System of Mice Irradiated by Carbon Ions[J]. Nuclear Physics Review, 2012, 29(3): 285-289. doi: 10.11804/NuclPhysRev.29.03.285

Citation:

WANG Ying, LU Dong, WEI Wei, JING Xi-gang, WANG Ju-fang, LI Wen-jian. Protective Effect of Yeast β-glucan on Immune System of Mice Irradiated by Carbon Ions[J]. Nuclear Physics Review, 2012, 29(3): 285-289. doi: 10.11804/NuclPhysRev.29.03.285

Protective Effect of Yeast β-glucan on Immune System of Mice Irradiated by Carbon Ions

doi: 10.11804/NuclPhysRev.29.03.285

1.
Lanzhou University, Lanzhou 730000, China;2.Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2012-09-20

Abstract

To detect Yeast β-glucan’s protective effect on mice’s immune system after C ion beam radiation， mice were used as the test model. We observed the weight， hair color and behavior of mice everyday within a 7 d period of time after irradiation. Meanwhile， the content of white blood cell， on the 2nd and 7th day after irradiation was detected. We detected the thymus and spleen SOD， GSHPX activity and MDA content of the mice on the 8th day. The results showed that yeast βglucan could reduce the rapid weight loss of mice， increase white blood cell content， increase thymus and spleen SOD， GSHPX activity， decrease MDA content of thymus and spleen. These results indicate that yeast βglucan can protect mice’s immune system against C ion beam radiation damage.

- Yeast β-glucan,
- ¹²C⁶⁺ion,
- radiation protection
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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Protective Effect of Yeast β-glucan on Immune System of Mice Irradiated by Carbon Ions

doi: 10.11804/NuclPhysRev.29.03.285

1. Lanzhou University, Lanzhou 730000, China;2.Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2012-09-20

Key words:

Abstract: To detect Yeast β-glucan’s protective effect on mice’s immune system after C ion beam radiation， mice were used as the test model. We observed the weight， hair color and behavior of mice everyday within a 7 d period of time after irradiation. Meanwhile， the content of white blood cell， on the 2nd and 7th day after irradiation was detected. We detected the thymus and spleen SOD， GSHPX activity and MDA content of the mice on the 8th day. The results showed that yeast βglucan could reduce the rapid weight loss of mice， increase white blood cell content， increase thymus and spleen SOD， GSHPX activity， decrease MDA content of thymus and spleen. These results indicate that yeast βglucan can protect mice’s immune system against C ion beam radiation damage.


Citation: