Clinical Research on Tumor Treatment with Heavy Ion Beam

YANG Lina; RAN Juntao; ZHANG Hong; LIU Yuanyuan; ZHANG Qiuning; GAO Liying; WANG Xiaohu

doi:10.11804/NuclPhysRev.30.02.166

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Article Navigation > Nuclear Physics Review > 2013 > 30(2): 166-173

YANG Lina, RAN Juntao, ZHANG Hong, LIU Yuanyuan, ZHANG Qiuning, GAO Liying, WANG Xiaohu. Clinical Research on Tumor Treatment with Heavy Ion Beam[J]. Nuclear Physics Review, 2013, 30(2): 166-173. doi: 10.11804/NuclPhysRev.30.02.166

Citation:

YANG Lina, RAN Juntao, ZHANG Hong, LIU Yuanyuan, ZHANG Qiuning, GAO Liying, WANG Xiaohu. Clinical Research on Tumor Treatment with Heavy Ion Beam[J]. Nuclear Physics Review, 2013, 30(2): 166-173. doi: 10.11804/NuclPhysRev.30.02.166

Clinical Research on Tumor Treatment with Heavy Ion Beam

doi: 10.11804/NuclPhysRev.30.02.166

School of Life Sciences, Lanzhou University, Lanzhou 730000, China;
Tumor Hospital of Gansu Province, Lanzhou 730050, China;

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2013-06-20

Abstract

This article reviews the advantages of heavy ion in physical, biological and clinical aspects, discusses the radio-biological basis of experiment research, and summarizes clinical results of heavy ion beam treatment on tumor at home and abroad. Japan has accepted and treated about 6000 cancer patients of different types with high local control rates and survival ones. Germany has achieved great success in head and neck tumor clinical treatment. Institute of Modern Physics, Chinese Academy of Sciences (IMP-CAS), Tumor Hospital of Gansu Province and Lanzhou General Hospital of PLA have begun clinical trial on heavy ion treatment of deep-seated tumors after the shallow-seated tumor therapy has been done at HIRFL (Heavy Ion Research Facility in Lanzhou). The treatment results of Tumor Hospital of
Gansu Province show that the objective response rate (CR+PR) is 71.4% and the rate of 1-2 levels radiation injury to skin reactions (erythema and desquamation) is 61.9% when we evaluate the 43 patients by means of maging. The results of case follow-up after treatment in 1 month indicate that the deep-seated tumor therapy with heavy ion beam has high local control rates without severe adverse effect.
- heavy ion,
- tumor,
- clinical research,
- local control rate
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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Clinical Research on Tumor Treatment with Heavy Ion Beam

doi: 10.11804/NuclPhysRev.30.02.166

School of Life Sciences, Lanzhou University, Lanzhou 730000, China;

Tumor Hospital of Gansu Province, Lanzhou 730050, China;

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2013-06-20

Key words:

Abstract: This article reviews the advantages of heavy ion in physical, biological and clinical aspects, discusses the radio-biological basis of experiment research, and summarizes clinical results of heavy ion beam treatment on tumor at home and abroad. Japan has accepted and treated about 6000 cancer patients of different types with high local control rates and survival ones. Germany has achieved great success in head and neck tumor clinical treatment. Institute of Modern Physics, Chinese Academy of Sciences (IMP-CAS), Tumor Hospital of Gansu Province and Lanzhou General Hospital of PLA have begun clinical trial on heavy ion treatment of deep-seated tumors after the shallow-seated tumor therapy has been done at HIRFL (Heavy Ion Research Facility in Lanzhou). The treatment results of Tumor Hospital of
Gansu Province show that the objective response rate (CR+PR) is 71.4% and the rate of 1-2 levels radiation injury to skin reactions (erythema and desquamation) is 61.9% when we evaluate the 43 patients by means of maging. The results of case follow-up after treatment in 1 month indicate that the deep-seated tumor therapy with heavy ion beam has high local control rates without severe adverse effect.

Citation: